Our goal is to determine the mechanistic properties of dynamin superfamily proteins (DSPs) through cryo-EM analysis and correlate them with their diverse cellular functions.
Select Publications
- Cryo-EM structures of membrane-bound dynamin in a post-hydrolysis state primed for membrane fission.
- Jimah JR, Kundu N, Stanton AE, Sochacki KA, Canagarajah B, Chan L, Strub MP, Wang H, Taraska JW, Hinshaw JE.
- Dev Cell (2024 Jul 22) 59:1783-1793.e5. Abstract/Full Text
- OPA1 helical structures give perspective to mitochondrial dysfunction.
- Nyenhuis SB, Wu X, Strub MP, Yim YI, Stanton AE, Baena V, Syed ZA, Canagarajah B, Hammer JA, Hinshaw JE.
- Nature (2023 Aug) 620:1109-1116. Abstract/Full Text
Lab Members
From left to right: Jonathan Harrison, Bertram Canagarajah (MICEF), Nidhi Kundu, Sarah Nyenhuis, Jenny Hinshaw, Vandana Mishra, Prasanthi Kunamaneni, Lindsey Njanja
Last Reviewed March 2024