Karen L. Teff, Ph.D.

- Co-Director: Office of Obesity Research
- Program Director: Division of Diabetes, Endocrinology, & Metabolic Diseases
Responsibilities & Activities
My portfolio includes basic and clinical research grants in the following areas: (1) the effects of bariatric surgery on diabetes and other outcomes associated with the pathophysiology of diabetes; (2) studies examining the mechanisms involved with, as well as the prevention, treatment, and pathophysiology of hypoglycemia; 3) autonomic control and contribution to metabolic dysfunction and 4) human sleep and circadian rhythms.
Research Programs
Clinical Research in Type 1 Diabetes
Determinants, etiology, progression, prevention, and treatment of type 1 diabetes in children and adults.
Clinical Research in Type 2 Diabetes
Progression and treatment of type 2 diabetes in children and adults.
Diabetes: Treatment, Prevention, & Complications
Metabolic Pathways
Studies on the pathways that are involved in intermediary metabolism as they impact endocrine and metabolic diseases.
Metabolism, Energy Balance & Obesity
Basic studies in non-human animals related to the neural control of energy balance and weight gain, loss and maintenance.
Pathophysiology of Diabetes & Metabolic Disease
Basic and clinical research that addresses the pathophysiology of metabolic diseases, including type 1 and type 2 diabetes.
Committees & Working Groups
- Management Committee, DEM
- Co-Director Office of Obesity Research
- Clinical Sciences Working Group, Member
- Trans-NIH SRCC, NIDDK representative
- Stakeholder Engagement Working Group
Select Experience
Director, Clinical and Translational Research Center, University of Pennsylvania, 2011-2013
Member, Monell Chemical Senses Center, 2006-2013
Director, Translational Research, Diabetes Research Center, University of Pennsylvania, 2006-2013
Member, Monell Chemical Senses Center, 1996-2004
Ph.D., McGill University, 1988