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  4. Terez Shea-Donohue, Ph.D.

Terez Shea-Donohue, Ph.D.

Basic and Translational Neurogastroenterology, Gastrointestinal Motility, Gastrointestinal Barrier Function, Mucosal Immunology and Inflammation

Responsibilities & Activities

As a Program Director in the Division of Digestive Diseases and Nutrition, I support basic and translational research related to neurogastroenterology, gastrointestinal (GI) and GI epithelial barrier function. My research portfolio covers the enteric nervous system including neuroimmune interactions; the brain-gut axis including the impact of neurodegenerative diseases on gastrointestinal physiology; basic and translational gastrointestinal motility; mechanisms of non-nutrient luminal sensing including those involved in pain; and changes in mucosal barrier function in response to inflammation or infection.  I also am involved in the NIH Common Fund Program SPARC (Stimulating Peripheral Activity to Relieve Conditions) Component 1 (Anatomical and Functional Mapping). This program supports investigations that detail the anatomical and functional mapping of neural circuitry mediating visceral organ pain with the goal of developing device-based therapeutics.

Research Programs

Gastrointestinal Immunology, Inflammation, & Inflammatory Diseases
Research on mucosal immunology, intestinal immunity, and inflammation in gastrointestinal diseases and conditions.

Gastrointestinal Microbiology & Infectious Diseases
Research on the gut microbiota and pathogenic organisms that reside in the gastrointestinal tract.

Gastrointestinal Neurobiology
Research on the neural control of the gastrointestinal system.

Gastrointestinal Physiology, Development, & Epithelial Biology
Basic, clinical, and translational research on GI development, diseases, and disorders.

Motility & Functional Gastrointestinal Disorders
Research on gastrointestinal motility and functional gastrointestinal disorders.

Committees & Working Groups

  • Trans NIDDK Women's Health Working Group, Member
  • Neuron-glia Interactions interest group, Member
  • Neurobiology Interest Group, Member
Last Reviewed March 2024