Seeking to understand the biology of sphingolipids with the goal of developing therapies for the diseases of sphingolipid metabolism.
Select Publications
- Deletion of GBA in neurons, but not microglia, causes neurodegeneration in a Gaucher mouse model.
- Duffy HBD, Byrnes C, Zhu H, Tuymetova G, Lee YT, Platt FM, Proia RL.
- JCI Insight (2024 Sep 17) Abstract/Full Text
- Sialidase NEU3 action on GM1 ganglioside is neuroprotective in GM1 gangliosidosis.
- Allende ML, Lee YT, Byrnes C, Li C, Tuymetova G, Bakir JY, Nicoli ER, James VK, Brodbelt JS, Tifft CJ, Proia RL.
- J Lipid Res (2023 Dec) 64:100463. Abstract/Full Text
Last Reviewed August 2024