Nuclear Organization & Gene Expression Section

of the Laboratory of Biochemistry & Genetics

Seeking to understand how higher-order chromatin structure influences gene expression.

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Chromatin insulator mechanisms ensure accurate gene expression by controlling overall 3D genome organization.
Bhattacharya M, Lyda SF, Lei EP.
Curr Opin Genet Dev (2024 May 28) 87:102208. Abstract/Full Text
NURF301 contributes to gypsy chromatin insulator-mediated nuclear organization.
Chen S, Rosin LF, Pegoraro G, Moshkovich N, Murphy PJ, Yu G, Lei EP.
Nucleic Acids Res (2022 Aug 12) 50:7906-7924. Abstract/Full Text
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Last Reviewed January 2024