Endocrine & Neural Dynamics Section

of the Laboratory of Biological Modeling

Applying mathematical modeling to the biophysical basis of insulin secretion in pancreatic beta cells and other neural and endocrine cells

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Pulsatile Basal Insulin Secretion Is Driven by Glycolytic Oscillations.
Fletcher PA, Marinelli I, Bertram R, Satin LS, Sherman AS.
Physiology (Bethesda) (2022 Jul 1) 37:0. Abstract/Full Text
Estimating insulin sensitivity and β-cell function from the oral glucose tolerance test: validation of a new insulin sensitivity and secretion (ISS) model.
Ha J, Chung ST, Springer M, Kim JY, Chen P, Chhabra A, Cree MG, Diniz Behn C, Sumner AE, Arslanian SA, Sherman AS.
Am J Physiol Endocrinol Metab (2024 Apr 1) 326:E454-E471. Abstract/Full Text
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Last Reviewed February 2024