Lab News

Members of the Usdin Lab 2022: Bruce Hayward, Karen Usdin, Xiaonan Zhao, Daman Kumari, Diego Jimenez and Carson Miller.

Work continued in 2021 despite the pandemic

Typical weekly lab meeting in 2021 thanks to COVID-19. Hot on the heels of our first efforts with gene knockouts (Carson!) and base-editing (Bruce!) using CRISPR-Cas9 technology in 2020 which demonstrated that all 3 MutL proteins were required for expansion and that the nuclease activity of MutLɣ was essential, Nan…