We study maternal factors that promote folliculogenesis, ensure fertilization, and sustain cleavage-stage development in mice.

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Reduced female fertility due to sequestration of RNA Pol II by pervasive transcription in exosome RNase-depleted oocytes.
Wu D, Dean J.
Cell Rep (2023 Oct 31) 42:113247. Abstract/Full Text
Chromatin remodeling of prostaglandin signaling in smooth muscle enables mouse embryo passage through the female reproductive tract.
Xin Q, Yu G, Feng I, Dean J.
Dev Cell (2023 Sep 25) 58:1716-1732.e8. Abstract/Full Text
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