Molecular Recognition Section

of the Laboratory of Bioorganic Chemistry

Using chemistry to discover new pharmacological tool compounds and translational candidate molecules, to investigate the role of purinergic signaling in health and disease.

Select Publications

Bridged Piperidine Analogues of a High Affinity Naphthalene-Based P2Y(14)R Antagonist.
Wen Z, Salmaso V, Jung YH, Phung NB, Gopinatth V, Shah Q, Patterson AT, Randle JCR, Chen Z, Salvemini D, Lieberman DI, Whitehead GS, Karcz TP, Cook DN, Jacobson KA.
J Med Chem (2022 Feb 24) 65:3434-3459. Abstract/Full Text
Structure-Activity Relationship of 3-Methylcytidine-5'-α,β-methylenediphosphates as CD73 Inhibitors.
Scortichini M, Idris RM, Moschütz S, Keim A, Salmaso V, Dobelmann C, Oliva P, Losenkova K, Irjala H, Vaittinen S, Sandholm J, Yegutkin GG, Sträter N, Junker A, Müller CE, Jacobson KA.
J Med Chem (2022 Feb 10) 65:2409-2433. Abstract/Full Text
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Staff of the Molecular Recognition Section

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