Publications

A selection of recent and significant publications can be viewed below.

View Dr. Bax's publications on ResearchGate.

View Dr. Bax's full publication list (log in using Google, Microsoft, etc. account for access).

Select Publications

Observation of β-Amyloid Peptide Oligomerization by Pressure-Jump NMR Spectroscopy.

Barnes CA, Robertson AJ, Louis JM, Anfinrud P, Bax A.

J Am Chem Soc (2019 Sep 4) 141:13762-13766. Abstract/Full Text

Transient lipid-bound states of spike protein heptad repeats provide insights into SARS-CoV-2 membrane fusion.

Chiliveri SC, Louis JM, Ghirlando R, Bax A.

Sci Adv (2021 Oct 8) 7:eabk2226. Abstract/Full Text

Concordance of X-ray and AlphaFold2 Models of SARS-CoV-2 Main Protease with Residual Dipolar Couplings Measured in Solution.

Robertson AJ, Courtney JM, Shen Y, Ying J, Bax A.

J Am Chem Soc (2021 Nov 24) 143:19306-19310. Abstract/Full Text

Hybrid measurement of respiratory aerosol reveals a dominant coarse fraction resulting from speech that remains airborne for minutes.

Shen Y, Courtney JM, Anfinrud P, Bax A.

Proc Natl Acad Sci U S A (2022 Jun 28) 119:e2203086119. Abstract/Full Text

Experimental NOE, Chemical Shift, and Proline Isomerization Data Provide Detailed Insights into Amelotin Oligomerization.

Chiliveri SC, Shen Y, Baber JL, Ying J, Sagar V, Wistow G, Anfinrud P, Bax A.

J Am Chem Soc (2023 Aug 16) 145:18063-18074. Abstract/Full Text

Additional Publications

Quantitative (1)H Nuclear Magnetic Resonance Assay for the Rapid Detection of Pyrazinamide Resistance in Mycobacterium tuberculosis from Sputum Samples.

Lopez JM, Zimic M, Vallejos K, Sevilla D, Quispe-Carbajal M, Roncal E, Rodríguez J, Rodríguez J, Antiparra R, Arteaga H, Gilman RH, Maruenda H, Sheen P.

J Clin Microbiol (2023 May 23) 61:e0152222. Abstract/Full Text

NMR Observation of Sulfhydryl Signals in SARS-CoV-2 Main Protease Aids Structural Studies.

Robertson AJ, Ying J, Bax A.

Chembiochem (2022 Oct 6) 23:e202200471. Abstract/Full Text

Measuring the (3)J H(N)H(a) coupling by a simple 2D-intra-HNCA IP/AP-E.COSY with simultaneous encoding of (15)N chemical shift and (1)J H(a)C(a) evolution.

Lopez JM, Maruenda H.

J Magn Reson (2022 Feb) 335:107111. Abstract/Full Text

NUScon: a community-driven platform for quantitative evaluation of nonuniform sampling in NMR.

Pustovalova Y, Delaglio F, Craft DL, Arthanari H, Bax A, Billeter M, Bostock MJ, Dashti H, Hansen DF, Hyberts SG, Johnson BA, Kazimierczuk K, Lu H, Maciejewski M, Miljenović TM, Mobli M, Nietlispach D, Orekhov V, Powers R, Qu X, Robson SA, Rovnyak D, Wagner G, Ying J, Zambrello M, Hoch JC, Donoho DL, Schuyler AD.

Magn Reson (Gott) (2021) 2:843-861. Abstract/Full Text

Four-dimensional NOE-NOE spectroscopy of SARS-CoV-2 Main Protease to facilitate resonance assignment and structural analysis.

Robertson AJ, Ying J, Bax A.

Magn Reson (Gott) (2021) 2:129-138. Abstract/Full Text

SARS-CoV-2 transmission via speech-generated respiratory droplets.

Bax A, Bax CE, Stadnytskyi V, Anfinrud P.

Lancet Infect Dis (2021 Mar) 21:318. Abstract/Full Text

A lowly populated, transient β-sheet structure in monomeric Aβ(1-42) identified by multinuclear NMR of chemical denaturation.

Kakeshpour T, Ramanujam V, Barnes CA, Shen Y, Ying J, Bax A.

Biophys Chem (2021 Mar) 270:106531. Abstract/Full Text

Study of the Acetylation Pattern of Chitosan by Pure Shift NMR.

Lopez JM, Sánchez LF, Nakamatsu J, Maruenda H.

Anal Chem (2020 Sep 15) 92:12250-12256. Abstract/Full Text

Visualizing Speech-Generated Oral Fluid Droplets with Laser Light Scattering.

Anfinrud P, Stadnytskyi V, Bax CE, Bax A.

N Engl J Med (2020 May 21) 382:2061-2063. Abstract/Full Text

Conditional Disorder in Small Heat-shock Proteins.

Alderson TR, Ying J, Bax A, Benesch JLP, Baldwin AJ.

J Mol Biol (2020 Apr 17) 432:3033-3049. Abstract/Full Text

Modulating the Stiffness of the Myosin VI Single α-Helical Domain.

Barnes CA, Shen Y, Ying J, Bax A.

Biophys J (2020 Mar 10) 118:1119-1128. Abstract/Full Text

Protein structural changes characterized by high-pressure, pulsed field gradient diffusion NMR spectroscopy.

Ramanujam V, Alderson TR, Pritišanac I, Ying J, Bax A.

J Magn Reson (2020 Mar) 312:106701. Abstract/Full Text

Residual Dipolar Couplings for Resolving Cysteine Bridges in Disulfide-Rich Peptides.

Ramanujam V, Shen Y, Ying J, Mobli M.

Front Chem (2019) 7:889. Abstract/Full Text

Observation and Kinetic Characterization of Transient Schiff Base Intermediates by CEST NMR Spectroscopy.

Ramanujam V, Charlier C, Bax A.

Angew Chem Int Ed Engl (2019 Oct 21) 58:15309-15312. Abstract/Full Text

Protein NMR: Boundless opportunities.

Bax A, Clore GM.

J Magn Reson (2019 Sep) 306:187-191. Abstract/Full Text

Importance of time-ordered non-uniform sampling of multi-dimensional NMR spectra of Aβ(1-42) peptide under aggregating conditions.

Ying J, Barnes CA, Louis JM, Bax A.

J Biomol NMR (2019 Sep) 73:429-441. Abstract/Full Text

Remarkable Rigidity of the Single α-Helical Domain of Myosin-VI As Revealed by NMR Spectroscopy.

Barnes CA, Shen Y, Ying J, Takagi Y, Torchia DA, Sellers JR, Bax A.

J Am Chem Soc (2019 Jun 5) 141:9004-9017. Abstract/Full Text

Local unfolding of the HSP27 monomer regulates chaperone activity.

Alderson TR, Roche J, Gastall HY, Dias DM, Pritišanac I, Ying J, Bax A, Benesch JLP, Baldwin AJ.

Nat Commun (2019 Mar 6) 10:1068. Abstract/Full Text

The Role of Molecular Flexibility in Antigen Presentation and T Cell Receptor-Mediated Signaling.

Natarajan K, Jiang J, May NA, Mage MG, Boyd LF, McShan AC, Sgourakis NG, Bax A, Margulies DH.

Front Immunol (2018) 9:1657. Abstract/Full Text

Monitoring (15)N Chemical Shifts During Protein Folding by Pressure-Jump NMR.

Charlier C, Courtney JM, Alderson TR, Anfinrud P, Bax A.

J Am Chem Soc (2018 Jul 5) 140:8096-8099. Abstract/Full Text

Accurate Measurement of Residual Dipolar Couplings in Large RNAs by Variable Flip Angle NMR.

Marchant J, Bax A, Summers MF.

J Am Chem Soc (2018 Jun 6) 140:6978-6983. Abstract/Full Text

Study of protein folding under native conditions by rapidly switching the hydrostatic pressure inside an NMR sample cell.

Charlier C, Alderson TR, Courtney JM, Ying J, Anfinrud P, Bax A.

Proc Natl Acad Sci U S A (2018 May 1) 115:E4169-E4178. Abstract/Full Text

Isoindole Linkages Provide a Pathway for DOPAL-Mediated Cross-Linking of α-Synuclein.

Werner-Allen JW, Monti S, DuMond JF, Levine RL, Bax A.

Biochemistry (2018 Mar 6) 57:1462-1474. Abstract/Full Text

Propensity for cis-Proline Formation in Unfolded Proteins.

Alderson TR, Lee JH, Charlier C, Ying J, Bax A.

Chembiochem (2018 Jan 4) 19:37-42. Abstract/Full Text

Prediction of nearest neighbor effects on backbone torsion angles and NMR scalar coupling constants in disordered proteins.

Shen Y, Roche J, Grishaev A, Bax A.

Protein Sci (2018 Jan) 27:146-158. Abstract/Full Text

Monitoring Hydrogen Exchange During Protein Folding by Fast Pressure Jump NMR Spectroscopy.

Alderson TR, Charlier C, Torchia DA, Anfinrud P, Bax A.

J Am Chem Soc (2017 Aug 16) 139:11036-11039. Abstract/Full Text

Sparse multidimensional iterative lineshape-enhanced (SMILE) reconstruction of both non-uniformly sampled and conventional NMR data.

Ying J, Delaglio F, Torchia DA, Bax A.

J Biomol NMR (2017 Jun) 68:101-118. Abstract/Full Text

An allosteric site in the T-cell receptor Cβ domain plays a critical signalling role.

Natarajan K, McShan AC, Jiang J, Kumirov VK, Wang R, Zhao H, Schuck P, Tilahun ME, Boyd LF, Ying J, Bax A, Margulies DH, Sgourakis NG.

Nat Commun (2017 May 16) 8:15260. Abstract/Full Text

A natural product inhibits the initiation of α-synuclein aggregation and suppresses its toxicity.

Perni M, Galvagnion C, Maltsev A, Meisl G, Müller MB, Challa PK, Kirkegaard JB, Flagmeier P, Cohen SI, Cascella R, Chen SW, Limbocker R, Sormanni P, Heller GT, Aprile FA, Cremades N, Cecchi C, Chiti F, Nollen EA, Knowles TP, Vendruscolo M, Bax A, Zasloff M, Dobson CM.

Proc Natl Acad Sci U S A (2017 Feb 7) 114:E1009-E1017. Abstract/Full Text

A Role for Neuronal Alpha-Synuclein in Gastrointestinal Immunity.

Stolzenberg E, Berry D, Yang D, Lee EY, Kroemer A, Kaufman S, Wong GCL, Oppenheim JJ, Sen S, Fishbein T, Bax A, Harris B, Barbut D, Zasloff MA.

J Innate Immun (2017) 9:456-463. Abstract/Full Text

Nuclear Magnetic Resonance Observation of α-Synuclein Membrane Interaction by Monitoring the Acetylation Reactivity of Its Lysine Side Chains.

Lee JH, Ying J, Bax A.

Biochemistry (2016 Sep 6) 55:4949-59. Abstract/Full Text

ARTSY-J: Convenient and precise measurement of (3)JHNHα couplings in medium-size proteins from TROSY-HSQC spectra.

Roche J, Ying J, Shen Y, Torchia DA, Bax A.

J Magn Reson (2016 Jul) 268:73-81. Abstract/Full Text

Toxic Dopamine Metabolite DOPAL Forms an Unexpected Dicatechol Pyrrole Adduct with Lysines of α-Synuclein.

Werner-Allen JW, DuMond JF, Levine RL, Bax A.

Angew Chem Int Ed Engl (2016 Jun 20) 55:7374-8. Abstract/Full Text

Studying Intrinsically Disordered Proteins under True In Vivo Conditions by Combined Cross-Polarization and Carbonyl-Detection NMR Spectroscopy.

Lopez J, Schneider R, Cantrelle FX, Huvent I, Lippens G.

Angew Chem Int Ed Engl (2016 Jun 20) 55:7418-22. Abstract/Full Text

Global Dynamics and Exchange Kinetics of a Protein on the Surface of Nanoparticles Revealed by Relaxation-Based Solution NMR Spectroscopy.

Ceccon A, Tugarinov V, Bax A, Clore GM.

J Am Chem Soc (2016 May 11) 138:5789-92. Abstract/Full Text

Observation of α-Helical Hydrogen-Bond Cooperativity in an Intact Protein.

Li J, Wang Y, Chen J, Liu Z, Bax A, Yao L.

J Am Chem Soc (2016 Feb 17) 138:1824-7. Abstract/Full Text

Quantitative evaluation of positive ϕ angle propensity in flexible regions of proteins from three-bond J couplings.

Lee JH, Ying J, Bax A.

Phys Chem Chem Phys (2016 Feb 17) 18:5759-70. Abstract/Full Text

Monomeric Aβ(1-40) and Aβ(1-42) Peptides in Solution Adopt Very Similar Ramachandran Map Distributions That Closely Resemble Random Coil.

Roche J, Shen Y, Lee JH, Ying J, Bax A.

Biochemistry (2016 Feb 9) 55:762-75. Abstract/Full Text

Accurate measurement of (3)J(HNHα) couplings in small or disordered proteins from WATERGATE-optimized TROSY spectra.

Roche J, Ying J, Bax A.

J Biomol NMR (2016 Jan) 64:1-7. Abstract/Full Text

A Novel MHC-I Surface Targeted for Binding by the MCMV m06 Immunoevasin Revealed by Solution NMR.

Sgourakis NG, May NA, Boyd LF, Ying J, Bax A, Margulies DH.

J Biol Chem (2015 Nov 27) 290:28857-68. Abstract/Full Text

Side Chain Conformational Distributions of a Small Protein Derived from Model-Free Analysis of a Large Set of Residual Dipolar Couplings.

Li F, Grishaev A, Ying J, Bax A.

J Am Chem Soc (2015 Nov 25) 137:14798-811. Abstract/Full Text

MERA: a webserver for evaluating backbone torsion angle distributions in dynamic and disordered proteins from NMR data.

Mantsyzov AB, Shen Y, Lee JH, Hummer G, Bax A.

J Biomol NMR (2015 Sep) 63:85-95. Abstract/Full Text

Homology modeling of larger proteins guided by chemical shifts.

Shen Y, Bax A.

Nat Methods (2015 Aug) 12:747-50. Abstract/Full Text

Complete dissociation of the HIV-1 gp41 ectodomain and membrane proximal regions upon phospholipid binding.

Roche J, Louis JM, Aniana A, Ghirlando R, Bax A.

J Biomol NMR (2015 Apr) 61:235-48. Abstract/Full Text

High accuracy of Karplus equations for relating three-bond J couplings to protein backbone torsion angles.

Li F, Lee JH, Grishaev A, Ying J, Bax A.

Chemphyschem (2015 Feb 23) 16:572-8. Abstract/Full Text