Symptoms & Causes for Exocrine Pancreatic Insufficiency

What are the symptoms of EPI?

Symptoms of exocrine pancreatic insufficiency (EPI) may include

In rare cases, EPI may lead to problems seeing at night or problems with your bones, such as low bone mass or osteoporosis.

What causes EPI?

Woman clutching her stomach.Symptoms of EPI may include cramps, discomfort, or pain in the abdomen.

Common causes of EPI include

Less common causes of EPI include

Last Reviewed January 2023
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This content is provided as a service of the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), part of the National Institutes of Health. NIDDK translates and disseminates research findings to increase knowledge and understanding about health and disease among patients, health professionals, and the public. Content produced by NIDDK is carefully reviewed by NIDDK scientists and other experts.