Treatment for Interstitial Cystitis

How do doctors treat IC?

Researchers have not found one treatment for interstitial cystitis (IC) that works for everyone. Doctors aim current treatments at relieving symptoms in each person on an individual basis.

A health care professional will work with you to find a treatment plan that meets your needs. Your plan may include

  • lifestyle changes
  • bladder training
  • physical therapy
  • medicines
  • bladder procedures

Some treatments may work better for you than others. You also may need to use a combination of these treatments to relieve your symptoms.

A health care professional may ask you to fill out a form, called a symptom scale, with questions about how you feel. The symptom scale may allow a health care professional to better understand how you are responding to treatment.

You may have to try several different treatments before you find one that works for you. Your symptoms may disappear with treatment, a change in what you eat, or without a clear reason. Even when your symptoms go away, they may return after days, weeks, months, or even years. Researchers do not know why. With time, you and your doctor should be able to find a treatment that gives you some relief and helps you cope with IC.

Lifestyle changes

Change your eating and drinking habits. Some people with IC find that certain foods or drinks trigger their symptoms. Others find no link between symptoms and what they eat. However, be sure to drink enough water to stay hydrated. Talk with your health care professional about how much liquid you should drink to prevent dehydration based on your health, how active you are, and where you live. Read more about eating, diet, and nutrition and how they relate to IC.

Quit smoking. Some people feel that smoking makes their IC symptoms worse. Researchers don’t know exactly how tobacco affects IC. However, smoking is a major cause of bladder cancer. If you smoke, one of the best things you can do for your bladder and overall health is to quit.

If you smoke or use other tobacco products, stop. Ask for help so you don’t have to do it alone. You can start by calling the national quitline at 1-800-QUITNOW or 1-800-784-8669. For tips on quitting, go to

Reduce stress. Researchers don’t think stress causes IC, yet stress can trigger painful symptom flares in some people with IC. If you feel stressed, try relaxation techniques and other activities that might soothe you, such as

  • looking at nature around you
  • listening to soft music
  • noticing smells around you
  • savoring each bite of a special treat
  • breathing gently

Be physically active. If you have IC, you may feel that the last thing you want to do is be physically active. However, many people feel that easy activities like walking or gentle stretching exercises help relieve symptoms.

Get support. Having the emotional support of family, friends, and other people with IC is a very important part of helping you cope. People who learn about the disorder and become involved in their own care do better than people who do not.

Bladder training

Bladder training may help your bladder hold more urine. People with bladder pain often get in the habit of using the bathroom as soon as they are aware of any need to go to avoid pain or urgency. They then feel the need to go before the bladder is really full. The body may get used to urinating often. Bladder training helps your bladder hold more urine before your body tells you to urinate.

Keep a bladder diary (PDF, 79 KB) to track how you are doing. Start by writing down the times when you urinate. For example, you may find that you return to the bathroom every 40 minutes. Try to wait a few more minutes and gradually stretch out the time between urinating. This may be easier if you are well hydrated. Read more about the importance of getting enough liquids in your diet.

If your bladder becomes painful, use the bathroom. You may find that your first urge to use the bathroom goes away if you ignore it. Find ways to relax or distract yourself when the first urge strikes.

After a week or two, you may be able to stretch the time out to 50 or 60 minutes, and you may find that the urge to urinate does not return as soon.

Bowel training

Your doctor may suggest that you try to train yourself to have a bowel movement at the same time each day to help you become more regular, also called bowel training. Consider keeping track of your bowel movements. Some people report that having regular bowel movements helps their IC symptoms. Talk with your health care professional if you are having bowel control problems, such as

Physical therapy

If you have IC symptoms or pelvic floor muscle spasm, your doctor may suggest that you work with a physical therapist who specializes in pelvic floor problems. The physical therapist will work to stretch tight pelvic floor muscles and help you keep them relaxed.


Your doctor may suggest that you take over-the-counter (OTC) pain medicine to help control mild bladder pain, including:

Talk with your doctor if you feel you need a stronger pain medicine. If you have severe pain, you may need your doctor to prescribe narcotic analgesics, or pain-relieving medicines, such as acetaminophen with codeine or longer-acting narcotics.

In some people, however, certain antidepressants, sinus medicines, and pain relievers may trigger symptom flares. Talk with your health care professional if these medicines make your IC worse.

Long-term use of pain medicines can be dangerous. Talk with your doctor about how to safely manage your chronic, or long-term, pain—possibly with the help of a pain specialist, a doctor who diagnoses, treats, and manages pain. You may also want to discuss alternatives to pain medicines or complementary pain medicines.

If lifestyle changes, bladder training, physical therapy, and pain medicines don’t do enough to relieve your IC symptoms, your doctor may prescribe other medicines, including:

All medicines, even OTC medicines, have side effects. Always consult a doctor before using any medicine or supplement for more than a few days.

A woman with medicines in her hand and a glass of water
If lifestyle changes, physical activity, and over-the-counter pain medicines don’t do enough to relieve your interstitial cystitis (IC) symptoms, your doctor may prescribe medicines for you.

Bladder instillation

Some people who have IC find relief after a treatment in which a doctor puts a small amount of liquid medicine into the bladder, called bladder instillation or a bladder wash or bath. The doctor guides a tube called a catheter into your bladder and slowly adds a liquid that eases irritation of the bladder wall. The liquid may be a compound called dimethyl sulfoxide (DMSO) or a solution that contains heparin, steroids, and a topical anesthetic, such as short-acting lidocaine, or long-acting marcaine.

You will be asked to keep the liquid in your bladder for about 15 minutes and then release it. You can have this treatment once every week or every other week for 1 or 2 months. You may not feel any better until the third or fourth treatment.

Bladder stretching

A doctor may use a procedure called bladder stretching, or hydrodistention, to treat your bladder pain, if only for a short time. Bladder stretching occurs when a doctor stretches your bladder by filling it with fluid. You will be given a local or general anesthesia to help you tolerate the bladder stretching.

Some people have temporary relief of their symptoms after this treatment. Researchers are not exactly sure why bladder stretching helps some people. Stretching may temporarily block pain signals sent by nerves in the bladder.

Sometimes your pain symptoms may temporarily get worse 4 to 48 hours after bladder stretching. However, your pain levels should return to your previous level or improve within 2 to 4 weeks.


Most people with IC do not require surgery. If you’ve tried every other option and your pain is still unbearable, you and your doctor may consider surgery to either

  • make the bladder larger, a procedure called bladder augmentation,
  • remove the bladder, called cystectomy, or
  • reroute the normal flow of urine, called urinary diversion

Talk with your doctor and family about the possible benefits and side effects of bladder surgery. Surgery does not cure the pain of IC in all cases.

Last Reviewed July 2017
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This content is provided as a service of the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), part of the National Institutes of Health. NIDDK translates and disseminates research findings to increase knowledge and understanding about health and disease among patients, health professionals, and the public. Content produced by NIDDK is carefully reviewed by NIDDK scientists and other experts.