Neurobiology of Obesity
Neurobiology of energy balance and clinical studies on non-homeostatic (extra-hypothalamic) contributions to obesity and diabetes.
The Neurobiology of Obesity and Metabolic Diseases program encompasses research on the regulation of body composition and peripheral metabolism by the brain. Specific areas of support within this area include neurotransmitters, neuropeptides and their receptors involved in regulating feeding behavior, energy sensing, satiety, and energy expenditure; interactions between the brain and peripheral metabolic signals, e.g., insulin, leptin, glucocorticoids, ghrelin; the neural integration of endocrine and metabolic signals; neural plasticity and functional remodeling associated with obesity and metabolic diseases, and the early development of neural networks that control feeding, satiety and peripheral metabolism.
NIDDK Program Staff
- Brad Cooke, Ph.D. Developmental Neuroendocrinology, Electrophysiology, and Cognitive Neuroscience
Recent Funding OpportunitiesView More Recent Funding Opportunities
NIDDK Central Repository Non-renewable Sample Access (X01 Clinical Trial Not Allowed)
PHS 2022-2 Omnibus Solicitation of the NIH, CDC and FDA for Small Business Innovation Research Grant Applications (Parent SBIR [R43/R44] Clinical Trial Not Allowed)
PHS 2022-2 Omnibus Solicitation of the NIH and CDC for Small Business Innovation Research Grant Applications (Parent SBIR [R43/R44] Clinical Trial Required)
PHS 2022-2 Omnibus Solicitation of the NIH for Small Business Technology Transfer Grant Applications (Parent STTR [R41/R42] Clinical Trial Not Allowed)
Promoting Organ and Tissue Donation Among Health Disparity Populations (R01 - Clinical Trial Optional)
View related clinical trials from ClinicalTrials.gov.
Study sections conduct initial peer review of applications in a designated scientific area. Visit the NIH’s Center for Scientific Review website to search for study sections.
NIDDK makes publicly supported resources, data sets, and studies available to researchers to accelerate the rate and lower the cost of new discoveries.
- Ancillary Studies to Major Ongoing Clinical Studies to extend our knowledge of the diseases being studied by the parent study investigators under a defined protocol or to study diseases and conditions not within the original scope of the parent study but within the mission of the NIDDK.
- NIDDK Central Repository for access to clinical resources including data and biospecimens from NIDDK-funded studies.
- NIDDK Information Network (dkNET) for simultaneous search of digital resources, including multiple datasets and biomedical resources relevant to the mission of the NIDDK.
Additional Research Programs
NIDDK supports the training and career development of medical and graduate students, postdoctoral fellows, and physician scientists through institutional and individual grants.Learn about NIDDK Research Training Programs
The NIDDK offers and participates in a variety of opportunities for trainees and researchers from communities underrepresented in the biomedical research enterprise. These opportunities include travel and scholarship awards, research supplements, small clinical grants, high school and undergraduate programs, and a network of minority health research investigators.Learn about NIDDK Diversity Programs
NIDDK participates in the Small Business Innovation Research (SBIR) and Small Business Technology Transfer (STTR) programs. These programs support innovative research conducted by small businesses that has the potential for commercialization.Learn about NIDDK Small Business Programs
Human Subjects Research
NIDDK provides funding for pivotal clinical research, from preliminary clinical feasibility to large multi-center studies.Learn about Human Subjects Research
NIDDK provides funding opportunities and resources to encourage translation of basic discoveries into novel therapeutics.Learn about NIDDK Translational Research Opportunities
Meetings & Workshops
Supports researchers with tools to enhance scientific rigor, reproducibility, and transparency, and provides a big data knowledge base for genomic and pathway hypothesis generation.