Diabetes: Treatment, Prevention, & Complications
The Diabetes: Treatment, Prevention, and Complications Program supports both basic and clinical studies aimed at addressing the prevention, treatment and pathophysiology of type 1 and type 2 diabetes across the lifespan.
The Diabetes: Treatment, Prevention, and Complications Program supports both basic and clinical studies aimed at addressing the prevention, treatment and pathophysiology of type 1 and type 2 diabetes across the lifespan. Studies on drug development or testing of medical therapies to treat type 1 and type 2 diabetes are included in this program. Studies specific to type 1 diabetes (T1DM) include those examining the cellular or immunological therapies to induce tolerance or arrest conversion from normal glucose homeostasis or dysglycemia to T1DM. Studies more specific to type 2 diabetes (T2DM) include those examining medical or surgical approaches that prevent diabetes, induce diabetes remission or improve dysglycemia. Studies relevant to both types of diabetes include those proposing lifestyle (diet and exercise) and other behavioral interventions to prevent or treat diabetes, such as approaches to improving health-related behaviors and enhancing diabetes self-management and other aspects of diabetes care. This Program encompasses basic, clinical and translational research on the pathophysiology and treatment of diabetic complications that apply to multiple tissues and organ systems. It includes tissue-specific research on diabetic wound healing, diabetic neuropathy, and central nervous system impairments including changes in cognition and/or brain structure and function, resulting from dysglycemia. The program also includes research on diabetes complications such as hypoglycemia and diabetic ketoacidosis, as well as studies addressing the impact of metabolic derangements in type 1 and type 2 diabetes mellitus on the skeleton.
NIDDK Program Staff
- Beena Akolkar, Ph.D. Clinical research in the prevention and immunopathogenesis of Type 1 Diabetes and the genetics and genomics of Type 1 and Type 2 Diabetes
- Guillermo A. Arreaza-Rubín, M.D. Diabetes and endocrine disease bioengineering and glucose sensing
- Miranda Broadney, M.D., M.P.H. Pediatrics, Pediatric Endocrinology, Clinical Management of Diabetes Mellitus, Insulin Resistance, Pediatric Obesity
- Henry B. Burch, M.D. Clinical studies utilizing existing digital health technology for the prevention and treatment of type 2 diabetes, clinical and basic science studies involving non-neoplastic disorders of the thyroid, clinical studies involving medical and novel dietary treatment of type 2 diabetes.
- Maureen Monaghan Center, Ph.D., CDCES Health Psychology, Behavioral Science, Clinical Management of Diabetes
- Shavon Artis Dickerson, Dr.P.H., M.P.H. Health Equity and Implementation Science
- Teresa Jones Diabetic Foot Consortium and other special projects in diabetes complications
- Jean M. Lawrence, Sc.D., M.P.H., M.S.S.A. Gestational diabetes; Type 2 diabetes in Adults; Epidemiology; Natural experiments
- Hanyu Liang, M.D., Ph.D. Hepatic Metabolism; Insulin Resistance; Type 2 Diabetes; Obesity; Bariatric Surgery
- Barbara Linder Type 2 diabetes in children and youth; human studies of metabolic imprinting
- Saul Malozowski, M.D., Ph.D., M.B.A. Neuroendocrinology of hypothalamic-pituitary axis, neuropeptide signaling and receptors; hormonal regulation of bone and mineral metabolism; HIV/AIDS-associated metabolic and endocrine dysfunction
- Pamela L. Thornton, Ph.D. Health Equity and Translational Research; Centers for Diabetes Translation Research (P30) Program
- Theresa Teslovich Woo, Ph.D. Human behavior, developmental cognitive neuroscience, and brain-based mechanisms involved in obesity and diabetes
Recent Funding OpportunitiesView More Recent Funding Opportunities
Human Islet Research Enhancement Center for the Human Islet Research Network (U24 Clinical Trial Not Allowed)
Limited Competition: Collaborative Partnership to Advance Global Health Research (U01 Clinical Trial Not Allowed)
Native American Research Centers for Health (NARCH) (S06 Clinical Trial Optional)
Integration of Novel Measures for Improved Classification of Type 2 Diabetes (U01, Clinical Trials Not Allowed)
Integration of Novel Measures for Improved Classification of Type 2 Diabetes Biostatistics Research Center (U01 Clinical Trial Not Allowed)
View related clinical trials from ClinicalTrials.gov.
Study sections conduct initial peer review of applications in a designated scientific area. View related study sections from the NIH's Center for Scientific Review.
NIDDK makes publicly supported resources, data sets, and studies available to researchers to accelerate the rate and lower the cost of new discoveries.
- Ancillary Studies to Major Ongoing Clinical Studies to extend our knowledge of the diseases being studied by the parent study investigators under a defined protocol or to study diseases and conditions not within the original scope of the parent study but within the mission of the NIDDK.
- NIDDK Central Repository for access to clinical resources including data and biospecimens from NIDDK-funded studies.
- NIDDK Information Network (dkNET) for simultaneous search of digital resources, including multiple datasets and biomedical resources relevant to the mission of the NIDDK.
Additional Research Programs
NIDDK supports the training and career development of medical and graduate students, postdoctoral fellows, and physician scientists through institutional and individual grants.Learn about NIDDK Research Training Programs
The NIDDK offers and participates in a variety of opportunities for trainees and researchers from communities underrepresented in the biomedical research enterprise. These opportunities include travel and scholarship awards, research supplements, small clinical grants, high school and undergraduate programs, and a network of minority health research investigators.Learn about NIDDK Diversity Programs
Small Business Programs
NIDDK participates in the Small Business Innovation Research (SBIR) and Small Business Technology Transfer (STTR) programs. These programs support innovative research conducted by small businesses that has the potential for commercialization.Learn about NIDDK Small Business Programs
Human Subjects Research
Human Subjects Research
NIDDK provides funding for pivotal clinical research, from preliminary clinical feasibility to large multi-center studies.Learn about Human Subjects Research
NIDDK provides funding opportunities and resources to encourage translation of basic discoveries into novel therapeutics.Learn about NIDDK Translational Research Opportunities
Meetings & Workshops
NIH Common Fund
Learn about current projects and view funding opportunities sponsored by the NIH Common Fund.
Planning to Apply? Register Early
Registration is required at eRA Commons and grants.gov and can take 4 weeks.